THURSDAY, OCTOBER 5, 2021 (HealthDay News )
According to researcher Willa Brenowitz, “generally, we discovered that the bigger the depressive symptoms, the poorer the cognitive, and the faster the rates of deterioration.”
Brenowitz, of the Department of Psychiatry and Behavioral Sciences at the University of California, San Francisco, continued, “Older adults considered to have moderate or high depression symptoms in early adulthood were found to endure a reduction in cognition over 10 years.”
A statistical model was created by the researchers to forecast the typical depression arc across 15,000 people, ranging in age from 20 to 89. The odds of cognitive impairment were shown to be 73% greater in a group of nearly 6,000 older persons who had early-adult depression symptoms and 43% higher in older adults who had depression symptoms.
According to Brenowitz, “several processes explain how depression might enhance dementia risk.” The hippocampus, a region of the brain crucial for creating, organizing, and storing new memories, is one of them. This is because dementia 0 of the central dementia 1 response system promotes the synthesis of the dementia 2 hormones glucocorticoids.
According to her, several research have linked depression to hippocampal shrinkage, and one study found that women lose volume at a higher pace than men.
Participants in this study had their depression levels checked. 13% of young individuals, 26% of persons in their mid-life, and 34% of participants over the age of 65 showed moderate to severe depression symptoms. Cognitive impairment was seen in over 1,200 subjects.
depression affects up to 20% of people at some point in their lifetime, thus it’s crucial to understand how it affects dementia 3, or mental, cognition. Dr. Kristine Yaffe, a researcher and member of the UCSF Department of Psychiatry and Behavioral Sciences, said as much.
Future research will be required to confirm these results, but until then, Yaffe stated in the announcement, “We should test and treat depression for various reasons.”
SOURCE: News release from the University of California, San Francisco, September 28, 2021
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